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Table 5 Significant enriched GO analysis of Down DEGs

From: Identification of potential biomarkers for aging diagnosis of mesenchymal stem cells derived from the aged donors

Ontology

ID

Description

GeneRatio

pvalue

p.adjust

BP

GO:0048568

embryonic organ development

25/135

5.47e-16

1.54e-12

BP

GO:0048562

embryonic organ morphogenesis

17/135

3.12e-11

4.39e-08

BP

GO:0001655

urogenital system development

16/135

2.18e-09

2.05e-06

BP

GO:0072001

renal system development

14/135

2.81e-08

1.98e-05

CC

GO:0062023

collagen-containing extracellular matrix

12/136

2.52e-05

0.006

CC

GO:0099056

integral component of presynaptic membrane

5/136

1.50e-04

0.012

CC

GO:0099055

integral component of postsynaptic membrane

6/136

1.61e-04

0.012

CC

GO:0098936

intrinsic component of postsynaptic membrane

6/136

2.02e-04

0.012

MF

GO:0005201

extracellular matrix structural constituent

12/130

2.80e-09

8.20e-07

MF

GO:0001227

DNA-binding transcription repressor activity, RNA polymerase II-specific

8/130

4.22e-04

0.062

MF

GO:0046875

ephrin receptor binding

3/130

9.96e-04

0.088

MF

GO:0004181

metallocarboxypeptidase activity

3/130

0.001

0.088

  1. Supplementary Table 1. Primers used for qPCR