Pre-clinical evaluation of the efficacy and safety of human induced pluripotent stem cell-derived cardiomyocyte patch

Table 1 Whole-genome sequencing results for hiPSCs (MCB), hiPSC-CMs, and hiPSC-CM patches

Sample	Number of SNVs/indels on CDS/splicing sites		Number of SNVs/indels on CDS/splicing sites (Census/Shibata’s list)	Number of CNVs on exons	Number of CNVs on exons (Census/Shibata’s list)
	WGS	WES	WGS/WES	WGS/SNP array	WGS/SNP array
MCB	15	11	0	0	0
MCB (expansion culture)	14	11	0	0	0
hiPSC-CMs	14	12	0	0	0
hiPSC-CM patch	14	11	0	0	0

CNV, copy number variation; hiPSC-CM, human induced pluripotent stem cell-derived cardiomyocyte; MCB, master cell bank; SNP, single-nucleotide polymorphism; SNV, single-nucleotide variant; Indels, insertions/deletions; WGS, whole-genome sequencing; WES, whole-exome sequencing

ISSN: 1757-6512