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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Cholangiocyte organoids to study drug-induced injury

Fig. 2

Effects of CPZ and BA cocktail on transporters. A, B CLCOs were pretreated with 30 μM CPZ with or without BA cocktail (BA 40× or 80×), for 24 (A) and 72 (B) h. Gene expression of the CLCOs transporters was measured by qPCR and normalized to the housekeeping genes. Data are presented as mean ± SD of five independent donors. Statistical differences between groups were tested using one-way ANOVA followed by Dunn’s test for multiple comparisons; *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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