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Table 2 IC50 of stimulation medium in cholangiocyte-like cell organoids (CLCOs)

From: Cholangiocyte organoids to study drug-induced injury

Compound solution

24 h (μM) (Mean ± SEM)

72 h (μM) (Mean ± SEM)

Cell viability

CPZ

101.1 ± 1.2

70.5 ± 1.1

CPZ + BA 40×

101.2 ± 1.1

50.3 ± 1.1

CPZ + BA 80×

101.7 ± 1.1

42.2 ± 1.1

Cytotoxicity (LDH release)

CPZ

80.6 ± 1.1

54.1 ± 1.1

CPZ + BA 40×

77.8 ± 1.1

42.3 ± 1.1

CPZ + BA 80×

77.2 ± 1.0

52.1 ± 1.1