Fig. 2

ASC-EVs treatment improves the motor performance of SMA mice. From P2/P4 to P10 the body weight measurements (A), tail suspension test (B), righting reflex test (C) and negative geotaxis test (D), were used to evaluate the motor performance of SMA mice treated with PBS (SMA-PBS, grey line) or ASC-EVs (SMA-EVs, blue line) and WT mice (black line). Overall, the results suggest an improvement in behavioural and motor performances of SMA-EVs mice compared to the SMA-PBS group