Table 1 Clinical phenotype of subjects used in the study
iPSCs | Control/Mutation | Disease condition | Age | Sex | iPS cell source | References |
|---|---|---|---|---|---|---|
Ctrl1 | Healthy control | None reported | 69 | F | Mesenchymal Stromal cells | [28] |
Ctrl2 (Resistant clone) | Healthy control | None reported | 6 | M | Fibroblasts | |
SFN | Nav1.9 (p.N1169S) and Nav1.8 (p.R923H) variant | Small fiber neuropathy | 69 | F | Fibroblasts | [25] |
IEM | Nav1.7 (p.Q875E) | Inherited erythromelalgia | 9 | F | Blood cells | – |
ANAT001 (RealDRG™) | Healthy control | None reported | Neonatal | F | Blood cells (cord blood derived) | – |