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Table 5 AP parameters—Chambers versus Anatomic

From: How to differentiate induced pluripotent stem cells into sensory neurons for disease modelling: a functional assessment

Parameters

Ctrl1 (Chambers)

Ctrl1 (Anatomic)

DIV14

DIV 28

DIV 35

DIV 14

DIV 28

DIV 35

RMP, mV

− 62.8 ± 2.6 (7)

− 76.1 ± 3.0a (5)

− 77.4 ± 1.3b (5)

− 68.3 ± 2.3 (5)

− 72.6 ± 2.5 (6)

− 71.9 ± 1.7 (6)

Cell capacitance, pF

9.8 ± 0.8c (7)

55.2 ± 4.4 d (5)

103.3 ± 14.3e (5)

8.0 ± 0.3 (5)

16.5 ± 3.8f (6)

18.3 ± 1.9g (6)

  1. Data as Mean ± SEM
  2. a,bp < 0.05 versus DIV 14 Ctrl1 (Chambers)
  3. c,dp < 0.05 versus DIV 35 Ctrl1 (Chambers)
  4. ep < 0.05 versus DIV 14 Ctrl1 (Chambers)
  5. fp < 0.05 versus DIV 28 Ctrl1 (Chambers)
  6. gp < 0.05 versus DIV 35 Ctrl1 Chambers)
  7. The values in brackets indicate the sample number, DIV—Days in vitro
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Stem Cell Research & Therapy

ISSN: 1757-6512