Fig. 5
From: Efficacy and safety of mesenchymal stem cell therapy for ovarian ageing in a mouse model
Immunogenicity study and biodistribution study of MSC transplantation. A The number of WBC (white blood cells), Neu (neutrophils), Lym (lymphocytes), Mon (monocytes), Eos (eosinophils) and Bas (basophils) in the mouse serum on Day 1, Day 3 and Day 6. B The concentration of immune molecules (IL-10, TNF-α, IFN-γ) in the serum of mice on Day 6. C Images of UC-MSCs under bright field (top) and green fluorescence (bottom) after PKH67 fluorescent dye labelling. D Representative images of ovary, uterus and spleen sections showing UC-MSC distribution on Day 1 and Day 7 after injection. E Images of AD-MSCs under bright field (top) and green fluorescence (bottom) after PKH67 fluorescent dye labelling. F Representative images of ovary, uterus and spleen sections showing AD-MSC distribution on Day 1 and Day 7 after injection. The error bars indicate SD. *p < 0.05