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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Combination of bone marrow mesenchymal stem cells and moxibustion restores cyclophosphamide-induced premature ovarian insufficiency by improving mitochondrial function and regulating mitophagy

Fig. 6

BMSCs-MOX mitigates mitochondrial damage and suppress mitophagy. A ROS production. Histograms show the mean fluorescence index (MFI) of DCF-DA levels in each group (n = 6). B Representative pictures of JC-1 and red/green ratio (Q2/Q3) (n = 3). C ATP concentration (n = 6). D DRP1, PINK1, and Parkin protein levels (n = 3). Full-length blots are presented in Additional file 4: Fig. S2. E Representative IHC for DRP1 and PINK1 (n = 6), Bar: 50 μm. F MODs of DRP1 and PINK1. G Drp1, Pink1, and Parkin mRNA expression (n = 6). * p < 0.05, ** p < 0.01, *** p < 0.001; **** p < 0.0001

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Stem Cell Research & Therapy

ISSN: 1757-6512