Figure 4From: Generation of disease-specific induced pluripotent stem cells from patients with different karyotypes of Down syndromeThe induced pluripotent stem cells (iPSCs-DSs) have a methylation status similar to that of hESCs. The methylation status of the endogenous OCT4 promoter in iPSCs-DS and parental human dermal fibroblasts was analyzed with bisulfite sequencing. Open circles indicate unmethylated CpGs, and solid circles indicate methylated CpGs.Back to article page