Table 1 Summary of vertebrate haploid cells
From: Haploid embryonic stem cells serve as a new tool for mammalian genetic study
Cell type | Origin | Pluripotency | Germline competence | Dependent factors for self-renewal | Genome stability | Function as gametes |
|---|---|---|---|---|---|---|
Fish phES cells | Parthenogenetic haploid embryos | Yes | Yes | bFGF and LIF | Stable | Yes |
Mouse phES cells | Parthenogenetic haploid embryos | Yes | Yes | 2i and LIF | Stable, with auto-diploidization | Yes |
Mouse ahES cells | Androgenetic haploid embryos | Yes | Yes | 2i and LIF | Stable, with auto-diploidization | Yes |
Monkey phES cells | Parthenogenetic haploid embryos | Yes | ND | bFGF | Stable, with auto-diploidization | ND |
Human near-haploid cells | Tumors | No | No | ND | Unstable, with chromosome loss | No |