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Table 1 Baseline characteristics of participants

From: Safety and efficacy of umbilical cord tissue-derived mesenchymal stem cells in the treatment of patients with aging frailty: a phase I/II randomized, double-blind, placebo-controlled study

Characteristics

MSCs group (N = 15)

Placebo group (N = 15)

Age (years)

67.27 ± 5.23

69.27 ± 5.02

Sex (n, %)

 Male

5 (33.33)

7 (46.67)

 Female

10 (66.67)

8 (53.33)

BMI (kg/m2)

24.03 ± 2.89

24.95 ± 3.67

Fried frailty phenotype scale

2 (2, 2)

2 (2, 3)

Chronic conditions

 Hypertension (%)

4 (26.67)

7 (46.67)

 Dyslipidemia (%)

4 (46.67)

1 (6.67)

 Type 2 diabetes mellitus (%)

3 (20)

5 (33.33)

 Ischemic cardiomyopathy (%)

2 (13.33)

2 (13.33)

Medication

 Aspirin (%)

2 (13.33)

1 (6.67)

 ACEI/ARB (%)

2 (13.33)

4 (26.67)

 Calcium antagonists (%)

2 (13.33)

1 (6.67)

 Metformin (%)

1 (6.67)

2 (13.33)

 Other oral antidiabetics (%)

2 (13.33)

3 (20)

 Insulin (%)

2 (13.33)

2 (13.33)

 Stain (%)

5 (33.33)

1 (6.67)

Laboratory

 Hemoglobin (g/L)

135.80 ± 7.72

132.47 ± 13.71

 White blood cell count (109/L)

5.89 ± 1.37

5.69 ± 1.45

 Platelet count (109/L)

203.2 ± 42.75

206.4 ± 73.50

 AST (U/L)

23.07 ± 14.26

23.73 ± 8.68

 ALT (U/L)

22.73 ± 18.18

21.00 ± 12.62

 GFR (mL/min per 1.73 m2)

70.73 ± 13.98

75.93 ± 16.35

 FBG (mmol/L)

5.94 ± 1.41

5.89 ± 1.26

  1. Data are median (interquartile range, IQR), mean (standard deviation, SD), or n (%)