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Figure 7 | Stem Cell Research & Therapy

Figure 7

From: Rho kinase inhibitor Y-27632 promotes the differentiation of human bone marrow mesenchymal stem cells into keratinocyte-like cells in xeno-free conditioned medium

Figure 7

Y-27632 can act both directly and indirectly on bone marrow mesenchymal stem cells (BMSCs) to promote their differentiation into keratinocyte-like cells. mRNA expression of cytokeratin-5, cytokeratin-14, stratifin, involucrin, and filaggrin in BMSCs under different conditions is shown. BMSCs treated with MesenCult-XF medium were normalised to 1. Data are presented as the mean ± standard error of the mean. n = 3. **P <0.01 MXF versus keratinocyte-conditioned media, # P <0.05. KCM1, keratinocyte-conditioned medium collected from keratinocytes with no Y-27632 treatment; KCM2, keratinocyte-conditioned medium collected from keratinocytes treated with Y-27632; KCM1 + Y, KCM1 plus Y-27632; MXF, MesenCult-XF medium; MXF + Y, MesenCult-XF medium plus Y-27632.

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