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Figure 7 | Stem Cell Research & Therapy

Figure 7

From: Mesenchymal stem cell-derived microparticles ameliorate peritubular capillary rarefaction via inhibition of endothelial-mesenchymal transition and decrease tubulointerstitial fibrosis in unilateral ureteral obstruction

Figure 7

Endothelial-to-mesenchymal transition in UUO kidney. Confocal laser microscopy analysis shows representative images of CD31 and α-SMA double-staining in UUO kidneys treated with vehicle control, KMSC, KMSC-derived MP, and MP-RNase (A, CD31; red color, α-SMA; green color). Quantitative analysis of CD31 and α-SMA double-positive cells per field (white arrows) in UUO kidneys. Results are expressed as the mean ± SE of six different experiments. The Kruskal-Wallis test was performed; * P <0.05 versus vehicle control (B). White bar represents 20 μm. KMSC, kidney-derived mesenchymal stem cells; MPs, microparticles; SE, standard error; UUO, unilateral uretal obstruction; α-SMA, α-smooth muscle actin.

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Stem Cell Research & Therapy

ISSN: 1757-6512