Table 1 Motor performance after therapy with stem cells labeled by iron oxide nanoparticles in experimental designs of stroke

Wen et al. [33] (2014)

Rat (Sprague-Dawley)

MCDA

T (N/A)

In lab

26

Rat

NSC

5 × 10⁵

Str

2 d

N/A

N/A

Shichinohe et al. [17] (2013)

Rat (Wistar)

Lacunar

T (N/A)

Resovist

1

Rat

BMSC

5 × 10⁵

Str

7 d

N/A

N/A

Tarulli et al. [32] (2013)

Rat (Long Evans)

MCDA

P

MOC07F, Bang Lab.

18,8

Rat (femur and tibia)

BMSC

3 × 10⁶

V

3 d

N/A

N/A

Zhang et al. [16] (2013)

Mice (CD-1)

MCDA

T (5 mi)

In lab

5-33

Mice

NSC

5 × 10⁵

IC; V

1 d

N/A

N/A

Liu et al. [31] (2013)

Rat (Sprague-Dawley)

MCDA

T (5 mi)

In lab

N/A

Rat

NSC

3 × 10⁴

Str

2 d

N/A

N/A

Lu et al. [11] (2013)

Dog (Beagle)

MCDA

T (2 h)

In lab

N/A

Dog (bone marrow)

MSC

3 × 10⁶

IC

2 h

N/A

N/A

Kamiya et al. [30] (2013)

Rat (Sprague-Dawley)

MCDA

T (90 mi)

In lab

N/A

Rat (femur and tibia)

MSC

10⁷ (1 mL)

IC

90 mi

N/A

N/A

Riegler et al. [13] (2012)

Rabbit (New Zealand)

OAF

T (5 mi)

FluidMag-D, FluidMag-lipid, FluidMag-DEAE, FluidMag, Endorem, Resovist

16-56.0

Rabbit

MSC

10⁵ (300 μL)

V

5 mi

2.9 ± 0.93

1.6 ± 0.38

Detante et al. [29] (2012)

Rat (Sprague-Dawley)

MCDA

T (90 mi)

In lab

10.0

Human (bone marrow)

MSC

10⁵ (5 μL)

Str IC

7 d

3.3 ± 1.5

1.4 ± 0.8

Yang et al. [28] (2011)

Rat (Sprague-Dawley)

MCDA

T (2 h)

In lab

25

Human (bone marrow)

MSC

6 × 10⁵

IC

14 d

N/A

N/A

Wang et al. [15] (2011)

Mice (CD-1)

MCDA

P; T (30 mi)

In lab

N/A

Mice (femur and tibia)

MSC

5 × 10⁵ (1 μL)

Str

0 d

N/A

N/A

Gutiérrez-Fernández et al. [34] (2011)

Rat (Sprague-Dawley)

MCDA

P

Endorem

11.2

Rat (femur and tibia)

MSC

2 × 10⁶ (650 μL)

IC V

0 d

3.4 ± 0.89

1.7 ± 0.53

Vandeputte et al. [21] (2011)

Rat (Fisher 344)

FOT1

N/A

Resovist

27.9

Rat

rMAPC

10⁶ (1 μL)

Str

1 d

N/A

N/A

Reddy et al. [12] (2010)

Rabbit (New Zealand)

ICAO

P

Resovist

11.2

Human (bone marrow)

MSC

10⁶ (1 μL)

IC

4 d

N/A

N/A

PPA

Crabbe et al. [20] (2010)

Mice

FOT1

N/A

Resovist; Endorem; Sinerem

11.2-27.9

Mice

MSC

10⁴-5 × 10⁶

Str

2 d

N/A

N/A

Rat (Fisher 344)

Song et al. [27] (2009)

Rat (Sprague-Dawley)

MCDA

T (2 h)

Feridex

11.2

Human

NSC

4 × 10⁵ (1 μL)

Str

1 d

3.6 ± 2.1

2.3 ± 0.42

Daadi et al. [26] (2009)

Rat (Sprague-Dawley)

MCDA

T (30 mi; 1 h)

Feridex

11.2

Human

ESC

5 × 10⁴-10⁶ (1 μL)

Str

2 d

11.5 ± 7.2

32.4 ± 12.3

Lee et al. [19] (2009)

Rat (Wistar)

FOT2

N/A

MPIO

11.2-27.9

Human

MSC

2 × 10⁴

IC

2 d

N/A

N/A

Resovist

2 × 10⁶

V

Walczak et al. [25] (2008)

Rat (Wistar)

MCDA

T (2 h)

Feridex

11.2

Rat (bone marrow)

MSC

10⁶ (2 μL)

V

30 mi

N/A

N/A

Kim et al. [24] (2008)

Rat (Sprague-Dawley)

MCDA

T (2 h)

Feridex

11.2

Human

MSC

10⁵

IC

7d

N/A

N/A

Guzman et al. [23] (2008)

Rat (Sprague-Dawley)

MCDA

T (1 h)

Feridex

11.2

Mice

NSC

2 × 10⁵ (2 μL)

Str

−7 d

N/A

N/A

Rice et al. [14] (2007)

Mice (C57B/6)

MCDA

T (1 h)

Feridex

11.2

Mice

fMSC

5 × 10²

IHp

1 d

3.7 ± 0.99

2.3 ± 0.48

5 × 10³

Str

Jendelová et al. [18] (2004)

Rat (Wistar)

FOT2

N/A

Endorem

11.2

Rat

ESC

2 × 10⁵

IC

7 d

N/A

N/A

MSC

2 × 10⁶

V

Hoehn et al. [22] (2002)

Rat (Wistar)

MCDA

T (1 h)

Sinerem

20.0

N/A

ESC

2 × 3 × 10⁴

Str

14 d

N/A

N/A

CC