Figure 5From: Transplantation of cryopreserved human umbilical cord blood-derived endothelial progenitor cells induces recovery of carotid artery injury in nude rats Homing of transplanted EPCs and reendothelialization of injured arteries. (A) Evans blue staining identified segments of denuded (blue) and reendothelialized (white) surfaces, scale bar = 1 mm. (B) EPC transplantation promotes reendothelialization compared to the control group, n = 5. (C) More homing UCB-EPCs and HPB-EPCs were detected than PPB-EPCs, n = 5. (D) Scanning electron microscopy analysis. The regenerated endothelium appeared rough, whereas the surface of the normal endothelium was smooth and covered with a monolayer coat. D1, Control; D2, PPB-EPCs; D3, HPB-EPCs; D4, UCB-EPCs; D5, Normal endothelium. (E) Homing of transfused PPB-EPCs, HPB-EPCs, and UCB-EPCs was detected by DiI tracing and UEA co-staining in frozen sections. Scale bar = 100 μm. * P <0.05; # P <0.01, ** P <0.001; NS, not significant. EPCs, endothelial progenitor cells; HPB-EPCs, peripheral blood derived EPCs from healthy volunteers; PPB-EPCs, peripheral blood derived EPCs from patients; UCB, umbilical cord blood; UEA, ulex europaeus agglutinin.Back to article page