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Figure 5 | Stem Cell Research & Therapy

Figure 5

From: Transplantation of cryopreserved human umbilical cord blood-derived endothelial progenitor cells induces recovery of carotid artery injury in nude rats

Figure 5

Homing of transplanted EPCs and reendothelialization of injured arteries. (A) Evans blue staining identified segments of denuded (blue) and reendothelialized (white) surfaces, scale bar = 1 mm. (B) EPC transplantation promotes reendothelialization compared to the control group, n = 5. (C) More homing UCB-EPCs and HPB-EPCs were detected than PPB-EPCs, n = 5. (D) Scanning electron microscopy analysis. The regenerated endothelium appeared rough, whereas the surface of the normal endothelium was smooth and covered with a monolayer coat. D1, Control; D2, PPB-EPCs; D3, HPB-EPCs; D4, UCB-EPCs; D5, Normal endothelium. (E) Homing of transfused PPB-EPCs, HPB-EPCs, and UCB-EPCs was detected by DiI tracing and UEA co-staining in frozen sections. Scale bar = 100 μm. * P <0.05; # P <0.01, ** P <0.001; NS, not significant. EPCs, endothelial progenitor cells; HPB-EPCs, peripheral blood derived EPCs from healthy volunteers; PPB-EPCs, peripheral blood derived EPCs from patients; UCB, umbilical cord blood; UEA, ulex europaeus agglutinin.

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