Figure 6From: Interaction between mesenchymal stem cells and endothelial cells restores endothelial permeability via paracrine hepatocyte growth factor in vitro Hepatocyte growth factor (HGF) neutralisation attenuated the restoration of the integrity of human pulmonary microvascular endothelial cell (HPMEC) monolayers in mesenchymal stem cell-endothelial cell (MSC-EC) interaction conditions. We found that the paracellular and transcellular permeability in the anti-HGF antibody (Ab) group was significantly increased over control (without anti-HGF Ab) (n = 3, P <0.05) (A, B), suggesting that human MSCs restored the integrity of HPMEC monolayers in MSC-EC interaction by paracrine HGF. (n=3, ** p < 0.01 vs. group LPS; # p<0.05 # # p < 0.01 vs. group MSC-EC interaction) LPS, lipopolysaccharide.Back to article page