Skip to main content
Figure 7 | Stem Cell Research & Therapy

Figure 7

From: CCR5 facilitates endothelial progenitor cell recruitment and promotes the stabilization of atherosclerotic plaques in ApoE−/− mice

Figure 7

CCR5-overexpressing endothelial progenitor cell treatment decreased interleukin-6 (IL-6) and matrix metalloproteinase 9 (MMP9) expression on the atherosclerotic plaques. (A) Immunostaining of IL-6 on the aortic root plaques at 6 weeks after treatment with phosphate-buffered saline (PBS), Lenti-EGFP, or Lenti-CCR5. (B) Quantitative analysis of the IL-6 expression in (A) (n = 6, *P <0.05, **P <0.01). (C) Immunostaining of MMP9 on the aortic root plaques at 6 weeks after treatment with PBS, Lenti-EGFP, or Lenti-CCR5. (D) Quantitative analysis of the MMP9 expression in (C) (n = 6, *P <0.05, **P <0.01). Bars represent mean ± standard deviation. CCR5, chemokine (C-C motif) receptor 5; EGFP, enhanced green fluorescent protein; n.s., non-significant.

Back to article page