Skip to main content
Figure 6 | Stem Cell Research & Therapy

Figure 6

From: Microencapsulated equine mesenchymal stromal cells promote cutaneous wound healing in vitro

Figure 6

Conditioned medium (CM) from microencapsulated mesenchymal stromal cells (MSCs) promotes NBL-6 migration and alters gene expression (n = 3). (A) Migration distances of NBL-6 cells cultured in CM from encapsulated MSCs as compared with MSC CM in in vitro scratch assays. Data are expressed as micrometer per hour in 48 hours. (B) Fold change of mRNA, as detected by quantitative reverse transcription-polymerase chain reaction, in NBL-6 cells cultured with encapsulated MSC CM as compared with control MSC CM. Left panel shows genes involved in reduction of hypergranulation or enhancement of wound healing or both, and right panel shows genes that stimulate hypergranulation or delay wound healing or both. *P <0.05. COLIII, collagen type 3; CxCL10, CXC chemokine 10; IL, interleukin; MMP1, metallopeptidase 1; NBL-6, horse dermal fibroblast cell.

Back to article page