Figure 2
From: Adipose-derived stem cell-based treatment for acute liver failure
The survival rate and biochemical indices after adipose tissue-derived stem cell (ASC) treatment. (A) Survival curves of D-galactosamine (D-gal) induced acute liver failure in the ASC-treated group and the phosphate-buffered saline (PBS)-treated group. The survival rate of the ASC-treated group at each time point was prolonged significantly compared with the PBS-treated group (n = 15, P <0.05). (B) No significant difference of serum albumin (ALB) levels was observed between the PBS-treated group and the ASC-treated group (n = 5, P >0.05). (C) The serum alanine aminotransferase (ALT) level of the ASC treatment group (301.7 ± 116 U/L; 47 ± 9.1 U/L) was significantly lower than that of the PBS-treated group (506.7 ± 166 U/L; 112.5 ± 55.4 U/L) at 1 and 3 days, indicative of liver function improvement (n = 5, P <0.01). (D) The serum aspartic aminotransferase (AST) level of the ASC-treated group (1,186.7 ± 426.2 U/L; 128 ± 19.3 U/L) was significantly lower than that of the PBS-treated group (2,396.7 ± 743 U/L; 321.3 ± 185.7 U/L) at 1 and 3 days (n = 5, P <0.01).