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Table 2 The most important active modules and their participant regulators in the conversion of mouse fibroblasts into iNSCs

From: Predicting involvement of polycomb repressive complex 2 in direct conversion of mouse fibroblasts into induced neural stem cells

Comparisons

Active modules

Nodes

Transcription factors

iNSC versus fibroblast

83

Nr0b1, Suz12, Rad21, Pou5f1, Zic3.

90

Stat4, Nr0b1, Suz12, Rad21, Jarid2, Sall4, Pou5f1, Myb, Zic3, Gata3.

182

Nr0b1, Ezh2, Nanog, Rad21, Myb, Zic3, Stat4, Suz12, Sall4, Pou5f1, Sox2.

213

Nanog, Rad21, Zic3, Suz12, Wt1, Sall4, Cebpb, Tcf3, Sox2, Nr0b1, Ezh2, Myb, Pou5f1, Olig2, Tfcp2l1.

5

Sall4, Pou5f1, Nanog, Sox2.

  1. iNSCs, induced neural stem cells.