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Figure 9 | Stem Cell Research & Therapy

Figure 9

From: Predictions for optimal mitigation of paracrine inhibitory signalling in haemopoietic stem cell cultures

Figure 9

Comparison of growth model predictions with experimental data. Effect of diffusivity on the growth model predictions of fed-batch cultures in a 12 ml culture bag of initial media height h 0 = 0.33 mm (corresponding to 1 ml culture). Here the diffusivity D = 6.5 × 10−11 m2/second, and the experimental points are taken from Csaszar and colleagues [8]. The Csaszar model is defined by Equations (14) to (20) in Additional file 1. For finite diffusivity D, the system is governed by Equations (14) to (18), (24) and (25) in Additional file 1. The initial conditions for the growth model are defined in Equation (23) in Additional file 1, and the parameters are presented in Table 2.

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