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Figure 1 | Stem Cell Research & Therapy

Figure 1

From: Multiple intravenous injections of allogeneic equine mesenchymal stem cells do not induce a systemic inflammatory response but do alter lymphocyte subsets in healthy horses

Figure 1

Multiple allogeneic mesenchymal stem cell (MSC) injections do not induce anaphylaxis or alter leukocyte concentration. (A) There were no significant changes in temperature, heart rate, or respiration rate throughout the course of MSC administration. (B) White blood cell count (WBC) did not change throughout the course of the study. Neutrophil (C) and lymphocyte (D) counts did not change throughout the course of the study. These data demonstrate that multiple high-dose injections of allogeneic MSCs do not result in an anaphylactic response and do not elicit a change in leukocyte concentration. Data are presented as mean ± standard error of the mean. Grey boxes demonstrate the 95% confidence interval (CI) of the day 0 and control samples. AT, adipose tissue; BM, bone marrow; D, day.

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