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Figure 3 | Stem Cell Research & Therapy

Figure 3

From: Multiple intravenous injections of allogeneic equine mesenchymal stem cells do not induce a systemic inflammatory response but do alter lymphocyte subsets in healthy horses

Figure 3

Multiple allogeneic mesenchymal stem cell (MSC) injections increase CD8+ T-cell numbers. There were no significant changes in the percentages of circulating CD21+ B cells (A) or CD4+ T cells (B) following multiple injections of MSCs. However, CD8+ T-cell percentages increased significantly in horses injected with bone marrow (BM)-derived MSCs (12.46% at day 28 and 11.76% at day 35) compared with control (C). The increase in CD8+ T cells decreased the CD4/CD8 ratio significantly (D). Data are presented as mean ± standard error of the mean. Grey boxes demonstrate the 95% confidence interval (CI) of the day 0 and control samples. *P <0.05. AT, adipose tissue; D, day.

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Stem Cell Research & Therapy

ISSN: 1757-6512