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Figure 10 | Stem Cell Research & Therapy

Figure 10

From: Susceptibility of murine induced pluripotent stem cell-derived cardiomyocytes to hypoxia and nutrient deprivation

Figure 10

Mitochondrial potential analysis in induced pluripotent stem cell-derived cardiomyocytes (iPS-CMs) and neonatal cardiomyocytes (N-CMs). (A) Representative images of tetramethylrhodamine methyl ester (TMRM) staining of iPS-CMs and N-CMs after 3 hours hypoxia and glucose/serum deprivation (GSD) compared to normoxia control (21% O2, 15% fetal bovine serum and high glucose). Scale bar 100 μm. (B) Quantification of TMRM fluorescence intensity of cells cultured in normoxia versus cells cultured in hypoxia and GSD (# P < 0.001, versus normoxia control; ## P < 0.001, iPS-CMs versus N-CMs in normoxia).

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