Figure 14
Western blot analysis of STAT3, p-STAT3, Akt, p-Akt and PKCε. (A) Representative immunoblots of STAT3, p-STAT3, Akt, p-Akt and PKCε expression in induced pluripotent stem cell-derived cardiomyocytes in normoxia/full medium (21% O2, + fetal bovine serum (FBS) + glucose), in hypoxia and glucose/serum deprivation (GSD) (1% O2; −FBS, −glucose), and in hypoxia/GSD with mesenchymal stromal cell-conditioned medium (MSC-CoM) (1% O2; +MSC-CoM). (B-D) Corresponding densitometry data of hypoxia/GSD with and without MSC-CoM, expressed as the fold-change compared to normoxia/full medium data. *P ≤ 0.05, versus normoxia/full medium; # P ≤ 0.05, versus MSC-CoM.