Figure 4From: Adipose-derived mesenchymal stromal cells modulate tendon fibroblast responses to macrophage-induced inflammation in vitro Protein expression of inflammatory factors (A) TNFα and (B) IL-1β was determined after one or five days for TFs cultured with macrophages with and without ASCs. ASCs suppressed the effects of M1 macrophages on the secretion of pro-inflammatory factors after five days of co-culture. There was a significant effect of macrophage type for both factors at both timepoints, and a significant effect of ASCs on day 5 for both factors (* P <0.05; N = 5 to 6 for day 1, N = 4 for day 5). ASCs, adipose-derived mesenchymal stromal cells; TFs, tendon fibroblasts.Back to article page