Table 2 ASCs suppressed the effects of M1 and M0 macrophages on TF secretion of pro-inflammatory factors

Day 1

Mean

P Value

Mean

P Value

TNF

1.8 ± 1.6

0.620

−1.7 ± 0.3

0.060

IL-1b

3.4 ± 3.4

0.340

1.0 ± 0.6

0.510

COX2

−1.2 ± 0.2

0.230

−1.1 ± 0.3

0.440

MMP1a

−1.9 ± 0.2

0.020

−1.9 ± 0.3

0.060

MMP3

−1.9 ± 0.2

0.010

−1.1 ± 0.2

0.350

MMP13

−1.3 ± 0.6

0.220

−1.5 ± 0.3

0.150

COL1

1.3 ± 0.3

0.030

1.1 ± 0.3

0.660

COL3

1.3 ± 0.5

0.280

−1.1 ± 0.2

0.440

BGN

1.1 ± 0.1

0.250

−1.1 ± 0.3

0.520

DCN

1.2 ± 0.4

0.440

−1.2 ± 0.3

0.240

SCX

−1.8 ± 0.1

<0.001

−1.1 ± 0.1

0.100

TNMD

−1.5 ± 0.2

0.030

1.0 ± 0.1

0.580

Day 5

Mean

P Value

Mean

P Value

TNF

2.7 ± 1.9

0.160

−1.9 ± 0.3

0.140

IL-1b

3.7 ± 3.3

0.180

−1.8 ± 0.6

0.280

COX2

−1.0 ± 0.1

0.760

−10 ± 0.0

<0.001

MMP1a

−1.5 ± 0.3

0.240

−7.7 ± 0.1

0.060

MMP3

1.5 ± 0.2

0.050

−4.6 ± 0.2

0.050

MMP13

1.9 ± 0.4

0.040

5.0 ± 6.6

0.490

COL1

1.0 ± 0.1

0.940

1.8 ± 0.1

<0.001

COL3

1.4 ± 0.3

0.290

2.0 ± 0.8

0.140

BGN

1.3 ± 0.3

0.390

−1.2 ± 0.2

0.300

DCN

1.2 ± 0.1

0.280

1.0 ± 1.1

0.770

SCX

1.2 ± 0.1

0.150

−1.8 ± 0.1

0.030

TNMD

1.4 ± 0.1

0.100

1.2 ± 0.3

0.430