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Figure 2 | Stem Cell Research & Therapy

Figure 2

From: RETRACTED ARTICLE: Activation of Wnt/β-catenin signalling promotes mesenchymal stem cells to repair injured alveolar epithelium induced by lipopolysaccharide in mice

Figure 2

Effect of control mouse mesenchymal stem cells (mMSCs) or β-catenin-overexpressing mMSCs on the histopathology of lipopolysaccharide (LPS)-induced lung injury and survival over 14 days. (A) Histopathological analysis of lung tissues from mice of all the experimental groups were performed at days 3, 7 and 14 after the LPS challenge (haematoxylin and eosin staining, magnification 200×). (B) Quantification of lung injury showed a significant reduction in the severity of lung injury in the LPS + mMSC control and LPS + mMSC-Ctnnb1 mice. The change was more significant in the LPS + mMSC-Ctnnb1 group than in the LPS + mMSC control group; n = 6 at each time point for each group. The results are expressed as the mean ± standard deviation. *P < 0.05, versus normal saline (NS) + phosphate-buffered saline (PBS) group; # P < 0.05, versus LPS + PBS group; & P < 0.05, versus LPS + mMSC control group.

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Stem Cell Research & Therapy

ISSN: 1757-6512