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Table 2 Expression levels for regulated genes according to primary gene ontology function

From: Influence of vascular endothelial growth factor stimulation and serum deprivation on gene activation patterns of human adipose tissue-derived stromal cells

   Serum-deprived VEGF-stimulated
Gene ID Gene name FC 2 |FC| FC 2 |FC|
Adhesion     
CLSTN2 Calsyntenin 2 +2.375 +5.187 +2.456 +5.488
JAM2 Junctional adhesion molecule B +1.079 +2.112 NS NS
ITGB3 Integrin, beta 3 −0.709 −1.635 −1.040 −2.056
PODXL Podocalyxin-like protein 1 −1.126 −2.183 −1.066 −2.093
Extracellular matrix     
SMOC2 SPARC related modular calcium binding 2 +2.059 +4.167 +2.185 +4.548
SPON1 Spondin 1, F-spondin, extracellular matrix protein +1.120 +2.174 +1.600 +3.039
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif +1.136 +2.198 +1.213 +2.318
SGCD Sarcoglycan delta +1.027 +2.038 +0.989 +1.985
DPT Dermatopontin +0.978 +1.970 +1.006 +2.008
MFAP4 Microfibrillar-associated protein 4 +0.950 +1.933 +0.964 +1.951
PTPRB Protein tyrosine phosphatase, receptor type, B NS NS −0.9992 −1.999
TGM2 Transglutaminase 2 −1.063 −2.090 NS NS
MMP3 Matrix metallopeptidase 3 −1.493 −2.816 −1.499 −2.826
COL13A1 Collagen, type XIII, alpha 1 −1.1227 −2.178 −0.9474 −1.028
MMP1 Matrix metallopeptidase 1 −2.139 −4.405 NS NS
  1. Groups defined by Gene Enrichment Analysis linked with Kyoto Encyclopedia of Genes and Genomes library and gene ontology terms. Fold changes (FC) and consequently calculated amount of up (+) or down (−) regulation (2|FC|) of significant genes (P < 0.05) compared to adipose tissue-derived stromal cells (ASCs) in complete medium are listed for vascular endothelial growth factor (VEGF)-treated and serum-deprived ASCs FC >0.9. Most of the regulated genes are shared between groups, but have been assigned to the primary group for the sake of clarity. NS, not significant.