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Table 2 Proteins which concentrations differ significantly when harvested from C2C12-Luc-GFP and C2C12-Luc-GFP-HO1 cells

From: Myoblast-conditioned media improve regeneration and revascularization of ischemic muscles in diabetic mice

  Protein Fold of change HO-1:GFP Properties of protein Selected references
Angiogenesis Myogenic
Pro Anti Pro Anti
Downregulated in C2C12-Luc-GFP-HO1 cells PEDF only in GFP   +    [57,62]
BGN only in GFP   + +   [67-69]
FRP1 only in GFP +   +   [66,70]
Fibronectin 0.2 +   +   [65,71]
Upregulated in C2C12-Luc-GFP-HO1 cells PDI only in HO-1 +     [72]
PPIase A 2.59 +    + [58,73]
MIF 3.06 +    + [59,63]
Haptoglobin 1.72 +     [60]
Galectin-1 1.86 +   +   [61,64,74]
  1. Mass spectroscopy analysis. Major activities related to angiogenesis and myogenesis are indicated, based on selected references. BGN, biglycan; FRP1, follistatin-related protein 1; GFP, green fluorescent protein; HO-1, heme oxygenase-1; MIF, macrophage migration inhibitory factor; PDI, protein disulfide isomerase; PEDF, pigment epithelium derived factor; PPIase A, peptidyl-prolyl cis-trans isomerase A.