Figure 7
Effects of implantation of DFAT cells on degeneration of renal cortex in adriamycin-induced nephropathy. Wistar rats were nephrectomized and were injected without adriamycin (Control) or with 4 mg/kg BW adriamycin through the tail vein without DFAT cells (Saline) or with 106 DFAT cells injected through the renal artery (DFAT ia) or tail vein (DFAT iv) after nephrectomy. A) The paraffin sections of removed renal cortex were stained with hematoxylin and eosin (H & E). Renal cortical thickness was measured under high magnification (x400). B) Glomerular injury score (GIS). C) Tubulointerstitial injury score (TIS). Data are the mean ± SEM (n = 4). *P < 0.05 and **P <0.01 in the indicated columns. Bar = 50 μm. BW, body weight; DFAT, dedifferentiated fat; SEM, standard error of the mean.