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Figure 2 | Stem Cell Research & Therapy

Figure 2

From: Macrophage migration inhibitory factor confers resistance to senescence through CD74-dependent AMPK-FOXO3a signaling in mesenchymal stem cells

Figure 2

Reduced expression and release of macrophage migration inhibitory factor in aged mesenchymal stem cells. (A) Macrophage migration inhibitory factor (MIF) mRNA levels analyzed by quantitative real-time PCR in aged and young mesenchymal stem cells (MSCs). (B) Concentration of MIF in the culture medium, analyzed by enzyme-linked immunosorbent assay in cultures of aged and young MSCs. Each column represents mean ± standard deviation from three independent experiments; *P <0.05 versus aged.

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