Figure 2From: Macrophage migration inhibitory factor confers resistance to senescence through CD74-dependent AMPK-FOXO3a signaling in mesenchymal stem cellsReduced expression and release of macrophage migration inhibitory factor in aged mesenchymal stem cells. (A) Macrophage migration inhibitory factor (MIF) mRNA levels analyzed by quantitative real-time PCR in aged and young mesenchymal stem cells (MSCs). (B) Concentration of MIF in the culture medium, analyzed by enzyme-linked immunosorbent assay in cultures of aged and young MSCs. Each column represents mean ± standard deviation from three independent experiments; *P <0.05 versus aged.Back to article page