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Figure 4 | Stem Cell Research & Therapy

Figure 4

From: Three-dimensional spheroid cell culture of umbilical cord tissue-derived mesenchymal stromal cells leads to enhanced paracrine induction of wound healing

Figure 4

The secretion of growth factors involved in the wound-healing process was increased in UCX® spheroids. Hepatocyte growth factor (HGF), transforming growth factor (TGF)-β1, granulocyte-colony stimulating factor (G-CSF), vascular endothelial growth factor (VEGF)-A, fibroblast growth factor (FGF)-2 and interleukin (IL)-6 were quantified in two-dimensional conditioned medium (CM2D) and three-dimensional conditioned medium (CM3D) using a FlowCytomix™ kit. Keratinocyte growth factor (KGF) was quantified in CM2D and CM3D by enzyme-linked immunosorbent assay. Results are expressed as fold-increase of CM3D relative to CM2D. Data are shown in mean ± standard deviation; n = 3.

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Stem Cell Research & Therapy

ISSN: 1757-6512