Figure 8
Activation of Notch1 signalling favours cardiac differentiation of c-KitPOS/NKX2.5POS bone marrow mesenchymal stem cells. Positive immunofluorescence (IF) staining was assessed for cardiac troponin T (cTnT), smooth muscle cells (SM22α), and von Willebrand factor (vWF) in 10 representative fields of Jagged1-treated c-KitPOS/NKX2.5POS bone marrow mesenchymal stem cells. Ratios to 4′,6-diamidino-2-phenylindole-positive cells represent differentiation potentials for cardiomyocytes, smooth muscle cells, and endothelial cells.