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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: CXCL14 and MCP1 are potent trophic factors associated with cell migration and angiogenesis leading to higher regenerative potential of dental pulp side population cells

Fig. 6

Localization of chemokine (C-X-C motif) ligand 14 (CXCL14) and its receptor, CXCR4, related to the transplanted cells and the endogenous migrated cells in the regenerated pulp on day 7. a, b Immunostaining of CXCL14 (red) merged with glutamic-oxaloacetic transaminase 2 (GOT2) or bromodeoxyuridine (BrdU) (green) and Hoechst 33342 (blue) after transplantation of pulp CD31− side population (SP) cells. c-e In situ hybridization and immunohistochemical analysis of expression of C-X-C chemokine receptor type 4 (CXCR4) (red) merged with BrdU (green) after transplantation of conditioned media (CM) from pulp (c), bone marrow (d), and adipose CD31− SP cells (e). f Ratio of CXCR4-positive cell numbers to BrdU-positive cell numbers in regenerated pulp tissues. Data are expressed as mean ± standard deviation of four determinations. *P < 0.05

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