Fig. 2
Akt and ERK1/2 signal pathways, cell cyclins (cyclin D1/E) and cyclin-dependent kinase inhibitors (p21/p27) are involved in high density lipoprotein promoting mice adipose-derived stem cell proliferation. Western blot expression of various signal pathway molecules and cell cycle regulatory proteins of mice adipose-derived stem cells which were treated with high density lipoprotein (HDL) at different concentrations a and at various time points h. b p-Akt, c p-ERK, d cyclin D1, e cyclin E, f p21, g p27, i p-Akt, j p-ERK, k cyclin D1, l cyclin E, m p21, n p27. Results are the mean ± standard error of the mean of three experiments for each condition determined by densitometry relative to corresponding total protein/beta-actin. *P <0.05, **P <0.01, ***P <0.001