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Table 3 Bottom 10 expression genes analyzed by genome-wide expression profile chips in inflammatory bowel disease rats at 14 days after treatment with mesenchymal stem cell transplantation

From: Expression of Wnt and Notch signaling pathways in inflammatory bowel disease treated with mesenchymal stem cell transplantation: evaluation in a rat model

Gene ID

Official symbol

Official full name

Fold changes

679314

LOC679314

Hypothetical protein LOC679314

−22.54

24249

S100g

S100 calcium binding protein G

−8.58

298873

Slc7a15

Solute carrier family 7, member 15

−6.99

81828

Zp2

Zona pellucida glycoprotein 2

−5.99

287644

Phospho1

Phosphatase, orphan 1

−5.88

155205

Slc36a1

Solute carrier family 36, member 1

−5.51

500973

Slc37a2

Solute carrier family 37, member 2

−4.62

361296

Rnf125

Ring finger protein 125

−4.46

308134

Tmem35

Transmembrane protein 35

−4.31

113902

Ces3

Carboxylesterase3

−4.15

  1. In all 20 genes, atonal homolog 1 (Atoh1) and olfactomedin 4 (Olfm4) were upregulated and associated with the Notch signaling pathway. Wnt11 was downregulated and related to the non-canonical Wnt signaling pathway. Other genes involved in the Wnt/β-catenin signaling pathway, such as Wnt3a, Wnt5a, frizzled family receptor 3 (Fzd3), glycogen synthase kinase-3β (GSK-3β), β-catenin, myelocytomatosis oncogene (C-myc), cyclin D, T-cell factor 4 (Tcf4), and adenomatous polyposis coli (APC), were also detected