Fig. 1

Undifferentiated NSC abundantly expressed CXCR4. a Primary fetal rat NSC expressed SOX2 as a marker for undifferentiated cells (green); cells were counterstained with Hoechst (blue; scale bar represents 100 μm). b Staining for CXCR4 (red) revealed that the cytokine receptor was expressed abundantly on primary NSC; cells were counterstained with Hoechst (blue; scale bar represents 50 μm). c Treatment with 6.25 μg OPN for 24 h did not change the abundant expression of CXCR4 (red) on NSC (blue: counterstaining with Hoechst; scale bar represents 50 μm)