Fig. 4

Cardiac function analysis by magnetic resonance imaging. Left ventricular ejection fraction (LVEF) (a), cardiac output (CO) (b), and infarct size (c) at 48 h and 30 days after myocardial infarction (MI) and decellularized pericardial-derived scaffold implantation. Data for individual pigs (dots) are shown. P = 0.030 (a), P = 0.010 (b), and P = 0.007 (c). Representative turbo-spin-echo (d and e) and T1 short-axis delayed enhancement (f and g) images from one pig 48 h and 30 days after MI and decellularized pericardial-derived scaffold grafting. Arrows indicate MI in the left ventricular wall, and T1 images show healthy myocardium (black) and the MI with gadolinium retention (brilliant white)