Accession number | Name | Total number of peptides | iTRAQ 1 ratio PG/control | iTRAQ 2 ratio PG/control |
---|---|---|---|---|
Actin cytoskeleton organization | ||||
 gi|157951604 | Adenylyl cyclase-associated protein 1 | 9 | 1.80 | 1.81 |
 gi|6680924 | cofilin-1 | 22 | 2.63 | 2.63 |
 gi|6681069 | Cysteine and glycine-rich protein 1 | 9 | 0.41 | 0.44 |
 gi|62526118 | Cytoskeleton-associated protein 4 | 22 | 6.02 | 5.81 |
 gi|125347376 | Filamin-A | 123 | 0.06 | 0.06 |
 gi|145966915 | Filamin-B | 89 | 0.18 | 0.22 |
 gi|124487139 | Filamin-C | 51 | 0.42 | 0.44 |
 gi|130488506 | Four and a half LIM domains protein 3 | 8 | 0.39 | 0.34 |
 gi|61657921 | Kinesin-1 heavy chain | 14 | 0.49 | 0.44 |
 gi|6755040 | Profilin-1 | 19 | 2.90 | 2.94 |
 gi|10946578 | Thymosin beta-4 | 15 | 0.42 | 0.44 |
 gi|47894398 | Tropomyosin alpha-4 chain | 51 | 0.57 | 0.60 |
 gi|31982755 | Vimentin | 101 | 27.8 | 29.5 |
Alternative splicing | ||||
 gi|85060507 | Heterogeneous nuclear ribonucleoprotein A1 | 27 | 6.94 | 8.24 |
 gi|21313308 | Heterogeneous nuclear ribonucleoprotein M | 17 | 2.70 | 2.85 |
 gi|283436178 | Heterogeneous nuclear ribonucleoproteins C1/C2 | 10 | 1.82 | 1.85 |
 gi|6678143 | Lupus La protein homolog | 9 | 1.57 | 1.89 |
 gi|31560656 | Polyadenylate-binding protein 1 | 24 | 1.55 | 1.88 |
 gi|126157504 | Serine/arginine repetitive matrix protein 2 | 12 | 0.33 | 0.35 |
 gi|34328400 | Serine/arginine-rich splicing factor 1 isoform 1 | 12 | 0.58 | 0.63 |
 gi|153791358 | Splicing factor 3B subunit 1 | 7 | 0.50 | 0.52 |
 gi|268837785 | Splicing factor 3b, subunit 2 | 16 | 1.59 | 1.62 |
 gi|23956214 | Splicing factor, proline- and glutamine-rich | 22 | 1.48 | 1.45 |
ATP metabolism | ||||
 gi|6680748 | ATP synthase subunit alpha | 21 | 2.53 | 2.48 |
 gi|31980648 | ATP synthase subunit beta | 32 | 5.89 | 5,84 |
 gi|7949005 | ATP synthase-coupling factor 6 | 8 | 0.35 | 0.38 |
 gi|150456419 | ATP-dependent RNA helicase A | 10 | 0.52 | 0.45 |
 gi|134288917 | Cytoplasmic dynein 1 heavy chain 1 | 16 | 0.48 | 0.53 |
Calcium-mediated signalling | ||||
 gi|6996913 | Annexin A2 | 28 | 1.89 | 1.72 |
 gi|6753060 | Annexin A5 | 26 | 6.01 | 6.47 |
 gi|21704156 | Caldesmon 1 | 31 | 2.17 | 2.49 |
 gi|6753244 | Calmodulin | 22 | 0.31 | 0.31 |
 gi|6671664 | Calnexin | 14 | 1.62 | 2.44 |
 gi|21312564 | Calponin-3 | 15 | 2.01 | 1.79 |
 gi|6680836 | Calreticulin precursor | 31 | 3.37 | 3,98 |
 gi|31981086 | EF-hand domain-containing protein D2 | 6 | 0.39 | 0.40 |
 gi|6679465 | Glucosidase 2 subunit beta precursor | 9 | 0.59 | 0.69 |
 gi|33620739 | Myosin light polypeptide 6 | 24 | 0.69 | 0.39 |
 gi|6677833 | Protein S100-A10 | 11 | 0.28 | 0.31 |
 gi|6677691 | Reticulocalbin-1 precursor | 10 | 0.50 | 0.69 |
 gi|114205428 | Reticulocalbin-2 precursor | 12 | 0.48 | 0.45 |
 gi|188035858 | Reticulocalbin-3 precursor | 13 | 0.41 | 0.54 |
 gi|295054266 | Spectrin alpha chain, brain isoform 2 | 80 | 0.60 | 0.58 |
 gi|117938332 | Spectrin beta chain, brain 1 isoform 1 | 45 | 0.50 | 0.43 |
Cell adhesion | ||||
 gi|61743961 | AHNAK nucleoprotein isoform 1 | 265 | 0.63 | 0.62 |
 gi|6754508 | LIM and SH3 domain protein 1 | 15 | 0.55 | 0.59 |
 gi|225543161 | Lipoma-preferred partner homolog isoform 1 | 18 | 0.55 | 0.55 |
 gi|70778915 | Moesin | 41 | 3.31 | 2.80 |
 gi|33598964 | Myosin-10 | 42 | 0.18 | 0.19 |
 gi|114326446 | Myosin-9 isoform 1 | 127 | 0.05 | 0.04 |
 gi|254675244 | Plectin isoform 1 | 151 | 0.31 | 0.56 |
 gi|377835925 | Protein AHNAK2-like | 16 | 0.78 | 0.54 |
 gi|227116327 | Talin-1 | 42 | 0.25 | 0.24 |
 gi|6678347 | Thy-1 membrane glycoprotein preproprotein | 5 | 4.15 | 3.93 |
 gi|6756085 | Zyxin | 19 | 0.52 | 0.55 |
 gi|114326497 | Laminin subunit beta-1 | 5 | 0.34 | 0.37 |
 gi|31982030 | Rho GDP-dissociation inhibitor 1 | 10 | 2.60 | 2.49 |
DNA replication | ||||
 gi|6679299 | Prohibitin | 9 | 1.82 | 2.39 |
 gi|7242171 | Proliferating cell nuclear antigen | 10 | 1.73 | 1.78 |
Extracellular matrix organization | ||||
 gi|34328108 | Collagen alpha-1(I) chain precursor | 56 | 0.66 | 0.49 |
 gi|111120329 | Collagen alpha-2(I) chain precursor | 53 | 0.67 | 0.68 |
 gi|33859580 | Galectin-3 | 12 | 1.96 | 1.81 |
 gi|33859596 | Prolyl 4-hydroxylase subunit alpha-1 precursor | 14 | 1.89 | 1.89 |
Glycolysis | ||||
 gi|6679937 | Glyceraldehyde-3-phosphate dehydrogenase | 33 | 25.5 | 23.1 |
 gi|70778976 | Phosphoglycerate kinase 1 | 40 | 3.37 | 3.18 |
 gi|226958349 | Triosephosphate isomerase | 20 | 2.58 | 2.53 |
 gi|70794816 | Alpha enolase | 55 | 16.8 | 20.2 |
Golgi apparatus function | ||||
 gi|254750698 | Nucleobindin-1 isoform 1 precursor | 17 | 0.53 | 0.54 |
 gi|194440700 | Nucleobindin-2 isoform 1 precursor | 5 | 0.53 | 0.54 |
Lipid metabolism | ||||
 gi|6681137 | Acyl-CoA-binding protein isoform 2 | 10 | 0.29 | 0.29 |
 gi|63999380 | Alpha-2-macroglobulin receptor-associated | 4 | 0.40 | 0.42 |
 gi|313151222 | ATP-citrate synthase isoform 1 | 10 | 0.46 | 0.53 |
 gi|93102409 | Fatty acid synthase | 8 | 0.55 | 0.55 |
 gi|225735657 | Sulphated glycoprotein 1 isoform F preproprotein | 9 | 5.49 | 5.24 |
Lipid transport | ||||
 gi|19527028 | Vigilin | 15 | 1.52 | 1.47 |
 gi|38198665 | NSFL1 cofactor p47 | 13 | 0.69 | 0.64 |
Nuclear structure | ||||
 gi|162287370 | Prelamin-A/C isoform A | 47 | 4.62 | 4.79 |
 gi|7110705 | Prothymosin alpha | 7 | 0.42 | 0.43 |
Nucleosome assembly | ||||
 gi|7949045 | Histone H2A.Z | 6 | 1.73 | 1.49 |
 gi|13591862 | Protein SET isoform 1 | 21 | 0.22 | 0.27 |
Nucleotide biosynthesis | ||||
 gi|209862992 | Dihydropyrimidinase-related protein 3 isoform 1 | 18 | 1.95 | 1.75 |
 gi|377835587 | inosine-5′-monophosphate dehydrogenase 2-like | 9 | 1.47 | 1.68 |
Oxidation–reduction process | ||||
 gi|31542438 | Cytochrome b5 type B precursor | 6 | 3.05 | 3.20 |
 gi|112181182 | Cytochrome c oxidase subunit 5A | 12 | 0.35 | 0.28 |
 gi|6681095 | Cytochrome c, somatic | 9 | 0.44 | 0.41 |
 gi|112293264 | Protein disulphide-isomerase A3 precursor | 49 | 6.03 | 5.80 |
 gi|86198316 | Protein disulphide-isomerase A4 precursor | 27 | 1.55 | 1.61 |
 gi|42415475 | Protein disulphide-isomerase precursor | 44 | 1.86 | 1.87 |
 gi|6755911 | Thioredoxin | 10 | 0.47 | 0.47 |
Protein catabolic process | ||||
 gi|6679501 | 26S protease regulatory subunit 4 | 15 | 2.21 | 2.59 |
 gi|228008337 | 26S protease regulatory subunit 6A | 16 | 1.97 | 1.93 |
 gi|124248577 | 26S protease regulatory subunit 6B | 12 | 2.27 | 2.37 |
 gi|19882201 | 26S proteasome non-ATPase regulatory subunit | 9 | 0.54 | 0.52 |
 gi|6755212 | Proteasome activator complex subunit 1 | 12 | 0.60 | 0.58 |
Protein folding and stress response | ||||
 gi|6680309 | 10 kDa heat shock protein, mitochondrial | 8 | 0.34 | 0.34 |
 gi|183396771 | 60 kDa heat shock protein, mitochondrial | 46 | 23.9 | 13.9 |
 gi|115270960 | BAG family molecular chaperone regulator 3 | 9 | 0.57 | 0.59 |
 gi|6755863 | Endoplasmin precursor | 42 | 6.42 | 7.51 |
 gi|31981690 | Heat shock cognate 71 kDa protein | 68 | 14.4 | 19.9 |
 gi|6754254 | Heat shock protein HSP 90-alpha | 44 | 2.22 | 2.26 |
 gi|40556608 | Heat shock protein HSP 90-beta | 48 | 2.55 | 2.46 |
 gi|27229055 | Huntingtin-interacting protein K | 5 | 0.40 | 0.42 |
 gi|161353506 | Serpin H1 precursor | 22 | 2.44 | 2.39 |
 gi|162461907 | Stress-70 protein, mitochondrial | 52 | 2.05 | 2.04 |
 gi|126521835 | T-complex protein 1 subunit beta | 18 | 1.71 | 1.68 |
 gi|6671702 | T-complex protein 1 subunit epsilon | 16 | 1.59 | 1.51 |
 gi|6753324 | T-complex protein 1 subunit zeta | 11 | 1.66 | 1.75 |
Protein transport | ||||
 gi|28077049 | Charged multivesicular body protein 4b | 9 | 0.51 | 0.51 |
 gi|51491845 | Clathrin heavy chain 1 | 18 | 0.52 | 0.48 |
 gi|122939198 | Clathrin light chain A isoform c | 7 | 0.44 | 0.45 |
 gi|88014720 | Importin subunit beta-1 | 9 | 0.41 | 0.42 |
 gi|124486712 | Ribosome-binding protein 1 isoform a | 20 | 0.60 | 0.65 |
Regulation of apoptosis and cell death | ||||
 gi|226874906 | 14-3-3 protein epsilon | 13 | 2.01 | 1.62 |
 gi|6756041 | 14-3-3 protein zeta/delta isoform 1 | 15 | 2.55 | 2.61 |
 gi|6678682 | Galectin-1 | 31 | 0.70 | 0.59 |
 gi|329755243 | Gelsolin isoform 2 | 22 | 1.85 | 1.89 |
 gi|165932375 | Plasminogen activator-inhibitor 1 RNA-binding protein | 31 | 0.67 | 0.68 |
 gi|9790259 | Programmed cell death protein 5 | 8 | 0.49 | 0.35 |
 gi|6755963 | Voltage-dependent anion-selective channel protein 1 | 15 | 2.53 | 2.41 |
Regulation of canonical Wnt signalling | ||||
 gi|6679641 | Emerin | 8 | 2.87 | 3.42 |
 gi|7305075 | ras GTPase-activating protein-binding protein 1 | 16 | 2.25 | 1.99 |
 gi|158854016 | S-phase kinase-associated protein 1 | 7 | 0.50 | 0.50 |
Regulation of cell proliferation | ||||
 gi|124517663 | Annexin A1 | 28 | 2.44 | 1.88 |
 gi|110625813 | Astrocyte-derived neurotrophic factor precursor | 11 | 0.47 | 0.47 |
 gi|28461294 | Protein CDV3 isoform b | 8 | 0.52 | 0.57 |
 gi|356640163 | Serine hydroxymethyltransferase, mitochondrial | 17 | 1.90 | 1.72 |
 gi|6678483 | Ubiquitin-like modifier-activating enzyme 1 | 15 | 0.59 | 0.58 |
Transcription | ||||
 gi|188497724 | Hepatoma-derived growth factor | 12 | 0.55 | 0.50 |
 gi|84875537 | Nucleolin | 33 | 3.60 | 4.17 |
 gi|6679567 | Polymerase I and transcript release factor | 17 | 2.23 | 2.65 |
 gi|13386026 | UPF0568 protein C14orf166 homolog | 9 | 0.60 | 0.60 |
Translation and ribosome assembly | ||||
 gi|309266241 | 60S ribosomal protein L29-like | 4 | 1.90 | 1.90 |
 gi|309263511 | 60S ribosomal protein L32-like | 6 | 7.27 | 9.17 |
 gi|21426889 | 40S ribosomal protein S11 | 11 | 2.99 | 2.84 |
 gi|13386034 | 40S ribosomal protein S13 | 10 | 4.74 | 6.81 |
 gi|6677799 | 40S ribosomal protein S15 | 11 | 2.26 | 1.82 |
 gi|12963511 | 40S ribosomal protein S19 | 10 | 2.92 | 3.02 |
 gi|18087805 | 40S ribosomal protein S2 | 14 | 2.75 | 2.88 |
 gi|13195604 | 40S ribosomal protein S23 | 7 | 5.35 | 4.83 |
 gi|6755372 | 40S ribosomal protein S3 | 16 | 1.64 | 1.65 |
 gi|254553321 | 40S ribosomal protein S3a | 13 | 2.75 | 2.65 |
 gi|6677805 | 40S ribosomal protein S4, X isoform | 14 | 7.60 | 4.25 |
 gi|6677813 | 40S ribosomal protein S8 | 12 | 5.30 | 5.39 |
 gi|33504483 | 40S ribosomal protein S9 | 11 | 4.41 | 4.01 |
 gi|6671569 | 60S acidic ribosomal protein P0 | 10 | 1.40 | 1.56 |
 gi|83745120 | 60S acidic ribosomal protein P2 | 14 | 0.31 | 0.30 |
 gi|16418339 | 60S ribosomal protein L10 | 11 | 3.04 | 3.81 |
 gi|31981945 | 60S ribosomal protein L13a | 9 | 3.96 | 3.00 |
 gi|13385036 | 60S ribosomal protein L15 | 7 | 4.40 | 3.52 |
 gi|83699424 | 60S ribosomal protein L18 | 5 | 3.03 | 3.22 |
 gi|58037465 | 60S ribosomal protein L18a | 6 | 2.99 | 2.92 |
 gi|226958657 | 60S ribosomal protein L19 isoform 2 | 7 | 4.35 | 4.19 |
 gi|18250296 | 60S ribosomal protein L24 | 6 | 4.45 | 4.11 |
 gi|6677777 | 60S ribosomal protein L26 | 7 | 3.80 | 3.31 |
 gi|8567400 | 60S ribosomal protein L27 | 9 | 5.65 | 5.99 |
 gi|255308899 | 60S ribosomal protein L3 | 20 | 3.47 | 3.23 |
 gi|94386224 | 60S ribosomal protein L36-like | 4 | 9.03 | 8.15 |
 gi|30794450 | 60S ribosomal protein L4 | 20 | 5.75 | 5.20 |
 gi|23956082 | 60S ribosomal protein L5 | 10 | 2.04 | 1.32 |
 gi|84662736 | 60S ribosomal protein L6 | 11 | 7.24 | 8.24 |
 gi|31981515 | 60S ribosomal protein L7 | 9 | 5.65 | 6.23 |
 gi|7305443 | 60S ribosomal protein L7a | 9 | 6.30 | 6.42 |
 gi|6755358 | 60S ribosomal protein L8 | 7 | 8.87 | 6.51 |
 gi|14149647 | 60S ribosomal protein L9 | 9 | 1.81 | 2.29 |
 gi|254540168 | 78 kDa glucose-regulated protein precursor | 49 | 5.20 | 4.12 |
 gi|82617575 | Bifunctional glutamate/proline--tRNA ligase | 6 | 0.43 | 0.44 |
 gi|126032329 | Elongation factor 1-alpha 1 | 33 | 2.48 | 2.63 |
 gi|31980922 | Elongation factor 1-beta | 16 | 0.39 | 0.30 |
 gi|33859482 | Elongation factor 2 | 44 | 0.32 | 0.50 |
 gi|21450625 | Eukaryotic initiation factor 4A-I isoform 1 | 23 | 2.29 | 1.96 |
 gi|146219837 | Eukaryotic translation initiation factor 3 | 19 | 0.50 | 0.63 |
 gi|365906249 | Eukaryotic translation initiation factor 3 | 8 | 0.49 | 0.32 |
 gi|167234372 | Eukaryotic translation initiation factor 4B | 23 | 0.59 | 0.60 |
 gi|31712036 | Eukaryotic translation initiation factor 5A-1 | 26 | 0.53 | 0.54 |
 gi|94367038 | 40S ribosomal protein S6-like isoform 2 | 6 | 5.49 | 5.50 |
 gi|309264022 | 40S ribosomal protein SA-like | 16 | 3.02 | 4.32 |
 gi|149251177 | 60S ribosomal protein L13-like | 8 | 4.11 | 3.18 |
 gi|377837258 | 60S ribosomal protein L23-like | 8 | 3.83 | 3.84 |
 gi|63572172 | 60S ribosomal protein L27a-like | 4 | 6.99 | 5.21 |
 gi|37497112 | Putative RNA-binding protein 3 isoform 1 | 8 | 0.59 | 0.55 |
 gi|31982373 | rRNA 2′-O-methyltransferase fibrillarin | 8 | 2.15 | 2.07 |