Fig. 5
From: White matter injury restoration after stem cell administration in subcortical ischemic stroke
White matter-associated markers are enhanced in striatum after ADMSC therapy in subcortical stroke model. a Immunofluorescence images and b immunofluorescence quantification of white matter repair-associated markers (NF, MBP, Olig-2 and NogoA) at 7 and 28 days after treatment. c Western blot and d Western blot quantification showed increased levels of MBP in the treated group compared to controls at both 7 and 28 days (p < 0.05), as well as augmented levels of Olig-2, NF (p < 0.05) and a trend to decreased levels of NogoA. Data are shown as mean ± SEM; scale bars = 20 μm; *p < 0.05; n = 4 animals, 4 sections each per group. ADMSC adipose-derived mesenchymal stem cells, d days, MBP myelin basic protein, NF neurofilament, Nogo-A neurite outgrowth inhibitor, Olig-2 oligodendrocite transcription factor 2