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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Effect of a single injection of autologous conditioned serum (ACS) on tendon healing in equine naturally occurring tendinopathies

Fig. 3

Longitudinal sections of tendon biopsies from superficial digital flexor tendons with tendinopathy. a–d Histopathological specimens stained with haematoxylin & eosin using a 40× objective. Tendons of horses on day 36 after intralesional treatment with autologous conditioned serum (ACS) (horse no. 4793/10; a) and no treatment (control tendon, horse no. 6384/11; b). The number of round cell nuclei was higher in control tendons than in ACS-treated tendons 36 days after treatment. Scale bars = 10 μm. Tendon of horse no. 2241/09 1 day before (day 0, c) and 190 days after (d) intralesional treatment with ACS. Alignment of collagen fibres improved significantly between day 0 and day 190 after ACS treatment. Scale bars = 10 μm. Tendon of horse no. 2240/09 36 days (e) and 190 days (f) after intralesional treatment with ACS. Immunohistochemistry revealed a significant increase of collagen type I expression between day 36 and day 190 after ACS treatment. Scale bars = 20 μm

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Stem Cell Research & Therapy

ISSN: 1757-6512