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Table 1 Most abundant miRNAs in MSC exosomes and cells

From: Human bone marrow- and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive miRNA and tRNA species

Rank Most represented miRNA in exosomes Most represented miRNA in cells
miRNA rpm ASC exosomes miRNA rpm ASC cells
1 miR-486-5p 172,837 miR-21-5p 145,332
2 miR-10a-5p 117,453 miR-22-3p 92,902
3 miR-10b-5p 104,447 miR-10b-5p 82,089
4 miR-191-5p 92,545 miR-222-3p 74,725
5 miR-222-3p 49,405 miR-143-3p 73,794
6 miR-22-3p 37,205 let-7a-5p 71,686
7 let-7a-5p 28,814 miR-10a-5p 44,303
8 miR-21-5p 27,233 miR-92a-3p 33,827
9 miR-127-3p 27,071 let-7f-5p 33,248
10 miR-143-3p 22,579 let-7i-5p 22,624
11 miR-99b-5p 21,471 miR-127-3p 17,303
12 miR-100-5p 18,836 miR-148a-3p 17,109
13 miR-92a-3p 18,217 miR-26a-5p 16,127
14 let-7f-5p 17,589 miR-92b-3p 14,852
15 miR-92b-3p 16,124 miR-21-3p 14,548
16 miR-26a-5p 13,207 miR-221-3p 12,481
17 miR-146a-5p 12,212 miR-16-5p 11,544
18 miR-4485 10,656 miR-100-5p 11,180
19 miR-146b-5p 10,,558 miR-31-5p 9521
20 miR-151a-3p 10,262 miR-411-5p 8051
  miRNA rpm BMSC exosomes miRNA rpm BMSC cells
1 miR-143-3p 124,950 miR-143-3p 185,884
2 miR-10b-5p 103,485 miR-21-5p 150,993
3 miR-486-5p 91,274 miR-22-3p 105,358
4 miR-22-3p 74,730 let-7a-5p 91,387
5 miR-21-5p 47,445 miR-10b-5p 42,729
6 miR-222-3p 46,094 miR-222-3p 38,076
7 miR-191-5p 45,054 miR-27b-3p 35,496
8 miR-100-5p 41,668 let-7f-5p 29,054
9 let-7a-5p 38,486 let-7i-5p 21,993
10 miR-99b-5p 29,011 miR-26a-5p 21,934
11 miR-92a-3p 24,941 miR-100-5p 21,157
12 miR-127-3p 21,319 miR-127-3p 14,836
13 let-7f-5p 21,203 miR-148a-3p 12,789
14 miR-92b-3p 20,938 miR-92b-3p 12,306
15 miR-423-5p 19,807 miR-92a-3p 11,840
16 miR-10a-5p 14,716 miR-191-5p 11,384
17 miR-27b-3p 13,604 miR-21-3p 11,372
18 let-7i-5p 11,997 miR-125b-5p 10,699
19 miR-28-3p 10,554 let-7b-5p 9603
20 miR-125b-5p 10,378 miR-16-5p 9583
  1. miRNAs present only in the list of cellular or in the list of exosomal miRNAs are highlighted in bold
  2. ASC adipose-derived mesenchymal stem cell, BMSC bone marrow-derived mesenchymal stem cell, miRNA microRNA, MSC mesenchymal stem cell, rpm reads per million
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Stem Cell Research & Therapy

ISSN: 1757-6512