Condition | TNF-α | IFN-γ | IL-6 | IL-8 | IL-10 | IL-17A | IL-21 | TGF-β1 | HLA-G | |
---|---|---|---|---|---|---|---|---|---|---|
(pg/ml) | (pg/ml) | (pg/ml) | (pg/ml) | (pg/ml) | (pg/ml) | (pg/ml) | (pg/ml) | (ng/ml) | ||
Healthy mucosa | ctr-TCLs | 55.3 ± 20.1 | 478.9 ± 100.7 | 409.8 ± 100.3 | 2005.4 ± 380.7 | 9.8 ± 2.8 | 18.9 ± 4.5 | 45.9 ± 9.5 | 555.9 ± 74.4 | 0.2 ± 0.07 |
n.s. | p < 0.05 | p < 0.05 | p < 0.01 | p < 0.01 | p < 0.001 | p < 0.05 | n.s. | n.s. | ||
MSC:T 1:20 | 70.3 ± 17.9 | 998.4 ± 209.4 | 4690.5 ± 220.4 | 2499.7 ± 277.6 | 20.8 ± 5.7 | 18.6 ± 3.5 | 38.6 ± 9.8 | 499.2 ± 29.1 | 1.2 ± 0.4 | |
n.s. | p < 0.01 | n.s. | p < 0.01 | p < 0.01 | n.s. | p < 0.05 | p < 0.05 | n.s. | ||
Non inflamed Crohn’s mucosa | ctr-TCLs | 290.50 ± 108.4 | 654.65 ± 88.1 | 725.73 ± 117.9 | 2387.0 ± 328.4 | 11.5 ± 1.8 | 23.2 ± 2.9 | 57.5 ± 8.0 | 517.1 ± 26.9 | 1.2 ± 0.1 |
p < 0.05 | p < 0.01 | p < 0.05 | p < 0.001 | p < 0.001 | p < 0.001 | p < 0.01 | p < 0.05 | n.s. | ||
MSC:T 1:20 | 402.3 ± 109.7 | 1117.8 ± 156.5 | 5154.68 ± 855.2 | 2408.1 ± 389.7 | 23.8 ± 3.8 | 23.6 ± 2.7 | 45.2 ± 4.7 | 567.4 ± 128.1 | 1.4 ± 0.3 | |
n.s. | p < 0.05 | n.s. | p < 0.001 | p < 0.01 | p < 0.05 | p < 0.01 | p < 0.05 | p < 0.01 | ||
Inflamed Crohn’s mucosa | ctr-TCLs | 428.2 ± 175.8 | 998.4 ± 328.4 | 3331.1 ± 538.2 | 2623.3 ± 475.8 | 14.1 ± 3.3 | 36.5 ± 4.2 | 128.9 ± 9.3 | 853.2 ± 97.0 | 1.1 ± 0.3 |
p < 0.01 | p < 0.01 | p < 0.01 | p < 0.001 | p < 0.001 | p < 0.001 | p < 0.001 | p < 0.05 | n.s. | ||
MSC:T 1:20 | 827.4 ± 202.1 | 1290.3 ± 290.5 | 5468.4 ± 990.3 | 2318.9 ± 392.1 | 33.4 ± 7.3 | 13.2 ± 2.9 | 127.9 ± 8.3 | 1071.1 ± 197.7 | 1.3 ± 0.1 | |
n.s. | p < 0.05 | p < 0.01 | p < 0.001 | p < 0.01 | p < 0.01 | p < 0.05 | p < 0.05 | p < 0.01 |