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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: CDH1 and IL1-beta expression dictates FAK and MAPKK-dependent cross-talk between cancer cells and human mesenchymal stem cells

Fig. 6

Transfer of cellular components from cancer cells to hMSCs but no evidence of cell fusion during co-culture. a hMSCs (GFP-labeled) were co-cultured with MCF7 labeled with DiL (for 5 days) or DiD (for 7 days) and subsequently were subjected to FACS analysis. b hMSCs were cultured alone (left) or were cultured in the upper chamber, while MCF7 cells labeled with DiD were cultured in the lower chamber and then cells were subjected to FACS analysis. c hMSCs (GFP-labeled, panel 1) or MCF7 (mcherry-labeled, panel 2) were cultured alone or were co-cultured (panel 3) and subjected to FACS analysis. Similarly, co-cultured hMSCs and MCF7 cells were stained for ESA and were subjected to FACS analysis. ESA epithelial specific antigen, GFP green fluorescent protein, MSC mesenchymal (stromal) stem cell

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