Fig. 1

LacZ-positive cells are detected in the wound up to day 14 after moderate burn injury. LacZ-positive cells are present in the wound at day 7 (a, b) and day 14 (c, d). At day 7, substantial inflammatory infiltrate in the skin and loose connective tissue below the panniculus carnosus (a, b) are observed. By day 14, positive cells remain and some cells in the dermal layer are positive for LacZ. (c) Inset shows percentage of positive LacZ dermal cells at day 14 ± standard deviation. d Inset shows higher magnification of LacZ-positive dermal cells. At day 21 (e) and day 28 (f), LacZ-positive cells other than endothelial or immune cells are not detected. At day 14, 14 % ± 4.1 % of interfollicular dermal cells appear to be positive for LacZ (c). Arrows indicate LacZ-positive cells