Fig. 4

Let-7b-MSCs improved ischemic heart function. a Fibrosis area was determined using Masson’s trichrome staining (**p <0.001). b To track the transplanted cells, cells were stained with DAPI prior to transplantation. Three days after transplantation, the number of DAPI stained cells was counted (*p <0.05). c Angiogenesis was evaluated by CD31 (green, arrow) staining. d Caspase-3 (red, arrow) was stained as a marker of apoptosis. Scale bar = 50 μm. Quantitative data expressed as the mean ± standard deviation of at least three independent experiments