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Table 1 Markers and potential functions of native BM-MSCs

From: Where is the common ground between bone marrow mesenchymal stem/stromal cells from different donors and species?

In-vivo MSC marker Potential function on MSCs Host/model References
CD271 Osteogenesis Human, murine cell line [96]
  Interactions with other BM cells Human [51, 97]
MSCA-1/Stro-3/non-specific alkaline phosphatase Osteogenesis/mineralization Human [34, 98]
Stro-1 Migration/homing Human [99]
CD146 Related to MSC topography, interaction with other BM cells Human [24, 50, 54, 100]
Leptin R (CD295) Controlling bone–fat balance Mouse [60]
  Age-related Human [64]
PDGFRα (CD140a) Related to immaturity Mouse/human [48]/[65]
  Support HSCs Mouse/human [30]
  Early adipogenic commitment Mouse/human [101]
PDGFRβ (CD140b) Proliferation Human [61]
CD49a Receptor for collagen and laminin Human [39, 102, 103]
CD106 Migration Human [50, 51]
  Interaction with other BM cells   [51]
CD51 Interaction with HSCs Mouse/human [30]
CD200 Immunoregulation Human [104]
CD90 Interactions with other BM cells Human [39]
   Mouse [51]
  1. BM bone marrow, HSC hematopoietic stem cell, MSC mesenchymal stem/stromal cell, MSCA-1 mesenchymal stem cell antigen-1, PDGFR platelet-derived growth factor receptor