Fig. 6

hAEC transplantation increased the number of ovarian follicles and restored the fertility of chemoablated mice. A Bar graph illustrating body weight of experimental and control groups following hAEC transplantation. B The ovarian weight in different groups at 28 days after hAEC transplantation. C Histological analysis of ovaries in different groups at 28 days after hAEC transplantation. D The number of different stage follicles counted at 28 days after hAEC transplantation. E Bar graph representing the number of pups per pregnancy at the end of mating. Data are mean ± SEM; *p < 0.05 versus Sham; #p < 0.05 versus Cy. Scale bars in c = 500 μm (a–c), 200 μm (d–f), 100 μm (g–i), 50 μm (j–l). Cy chemoablated group (n = 6; n = 10 in E), Cy + hAECs hAEC-treated group (n = 6; n = 10 in E), Sham sham group (n = 6; n = 5 in E)